PRP for Arthritis St. Petersburg: Advanced Regenerative Joint Care

Three-time winner of Tampa Bay’s Best of the Best (2023, 2024, 2025)

Conditions We Treat with PRP for Arthritis

We provide focused regenerative care for foot and ankle arthritis that fails to improve with standard interventions.

Arthritis in the foot and ankle causes cartilage to wear down, joints to stiffen, and everyday movement to become painful. When anti-inflammatories, orthotics, or cortisone injections stop providing meaningful relief, platelet-rich plasma therapy offers a biological alternative that works with your body’s own healing mechanisms. At Align Foot & Ankle, we offer in-office PRP injections in St. Petersburg as a targeted, non-surgical option to reduce joint inflammation, slow degeneration, and help patients move with less pain.

Our PRP treatments are designed around clinical imaging, diagnostic insight, and real anatomical understanding of how arthritis progresses in the foot and ankle. We draw a sample of your blood, process it to concentrate the platelets, and inject it with precision directly into the arthritic joint. The entire procedure is completed in our St. Pete clinic and typically takes under an hour.

Why Choose Us for PRP Arthritis Treatment

Board-certified foot and ankle surgeon with years of advanced regenerative medicine experience.

Treating arthritis with PRP effectively requires more than a basic injection. It takes a surgeon who understands joint mechanics, knows precisely where to deliver the therapy, and can combine it with the right supportive treatments to maximize results.

Dr. Barnett is known for helping St. Petersburg patients find lasting relief from foot and ankle arthritis, including cases that had already failed physical therapy, cortisone shots, and other conservative approaches.

From the moment you walk through our doors, you’ll experience a level of compassion, precision, and personal attention that truly sets us apart.

A Full Range of Advanced Treatments for Arthritis & Joint Repair

We offer one of the most comprehensive selections of modern regenerative medicine and orthopedic options at our St. Petersburg clinic. This allows us to choose the ideal combination of treatments for your specific arthritis and give it the best chance to improve quickly, completely, and with lasting results. Every decision is made with precision, experience, and the goal of getting it right the first time.

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Our Values

We Put People First

We curate personalized experiences for individual needs. People are the heart behind everything we do.

Building Community

That small-town, southern-charm-feel lives here at Align and takes center stage. Community is at the core of who we are. We want our patients to know that we’re people they can trust. So, we get to know them – and before long, we’re family.

Open Channels of Communication

We strive to put our patients in positions that assure them they can safely come to us for anything. To do this, we make room for transparency and trust so that no need gets left behind.

Accessibility of Innovative Treatments & Devices

Quality trumps all. So, we use only the most sophisticated tools. Our groundbreaking technologies and innovative techniques keep us at the forefront of an essential industry.

Ease & Comfort

We’ve created a physical atmosphere that is functional and full of comfort. Our waiting rooms are designed to provide our patients with an extension of home – if even for a moment.

Meet Dr. Zachery P. Barnett, DPM: PRP & Arthritis Specialist

Dr. Zachery Barnett is a board-certified foot and ankle surgeon known for integrating advanced regenerative therapies, including platelet-rich plasma (PRP), into personalized care plans for patients dealing with arthritis across St. Petersburg. With a background in surgical training at the University of Louisville, a nationally recognized Level 1 Trauma Center, Dr. Barnett brings both technical precision and a conservative, biology-first mindset to the management of joint degeneration.

His interest in PRP for arthritis grew from years of treating patients with painful, stiff joints who wanted relief without rushing to fusion or replacement surgery. Rather than masking symptoms, he focuses on stimulating the joint’s own repair environment, reducing inflammation, protecting remaining cartilage, and improving mobility through targeted biologic therapy.

Today, Dr. Barnett works closely with each patient to understand the full picture of their arthritis: how far it has progressed, which joints are most affected, and whether PRP, combined with orthotics, bracing, or other regenerative tools, offers the most effective path forward. His goal is to preserve joint function and quality of life with precision, compassion, and evidence-based care.

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Get Help With PRP for Arthritis Today

Request an Appointment

At Align Foot and Ankle, we understand schedules are busy, and it can be hard to get an appointment. Let us know what you need and we will do everything we can to accommodate you.

PRP Arthritis Specialist, St. Petersburg, FL

Our St. Pete clinic is conveniently located in the heart of St. Petersburg, making expert PRP care for arthritis easily accessible to patients throughout the city and surrounding areas. We treat patients from across St. Pete, including downtown, Kenwood, Old Northeast, Shore Acres, Crescent Lake, Gulfport, and surrounding Pinellas County communities. Whether you’re local to St. Pete or traveling from nearby areas like Clearwater, Largo, or Seminole, we’re proud to be your trusted provider for PRP arthritis treatment in the foot and ankle.

Dr. Zachery Barnett is a board-certified foot and ankle surgeon offering specialized PRP therapy for arthritis in St. Petersburg. Many of our patients come to us with progressive joint pain, stiff ankles in the morning, aching big toe joints, midfoot soreness after walks, that hasn’t responded adequately to prior treatment. As a dedicated regenerative specialist in St. Pete, Dr. Barnett provides expert, results-driven PRP treatment plans tailored to the specific joint, severity, and lifestyle of each patient.

We understand the unique needs of this community, including the many active retirees and outdoor enthusiasts in St. Petersburg who refuse to let arthritis slow them down. We proudly offer advanced, non-surgical options that fit each patient’s goals and medical history.

If you’re looking for PRP for arthritis in St. Petersburg, regenerative joint care in St. Pete, or a trusted specialist near you, you’re in the right place. Our clinic combines advanced medical technology with old-fashioned attentiveness to provide real, lasting solutions. Whether you’re newly diagnosed or have been managing arthritis pain for years, we’re here to help you find relief, protect your joints, and move forward with confidence.

Many of our patients in St. Petersburg come to us with arthritis that hasn’t meaningfully improved with standard treatment. We specialize in diagnosing which joints are most involved, understanding the underlying mechanics contributing to wear, and treating the condition with biologics that give the joint its best chance at slowing deterioration. As a PRP arthritis specialist in St. Pete, Dr. Barnett takes a fully customized approach, using PRP injections, bone marrow concentrates, Class IV laser, bracing, and custom orthotics together for the most complete result possible. Whether you’re in downtown St. Petersburg or nearby neighborhoods like Gulfport or Treasure Island, we’re here to help you heal more fully and live more freely.